Brian Becknell Selected Research

Ribonuclease 7

1/2019	Analysis of the Ribonuclease A Superfamily of Antimicrobial Peptides in Patients Undergoing Chronic Peritoneal Dialysis.
1/2019	Ribonuclease 7 Shields the Kidney and Bladder from Invasive Uropathogenic Escherichia coli Infection.
1/2019	The Responses of the Ribonuclease A Superfamily to Urinary Tract Infection.
3/2016	A Review of Ribonuclease 7's Structure, Regulation, and Contributions to Host Defense.
1/2016	Insulin and the phosphatidylinositol 3-kinase signaling pathway regulate Ribonuclease 7 expression in the human urinary tract.
1/2015	Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract.

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Brian Becknell Research Topics

Disease

13	Infections 01/2019 - 01/2005
12	Neoplasms (Cancer) 09/2010 - 09/2002
9	Urinary Tract Infections (Urinary Tract Infection) 10/2020 - 05/2013
8	Pyelonephritis 01/2018 - 05/2013
5	Cicatrix (Scar) 01/2021 - 10/2016
5	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 07/2005 - 09/2002
4	Inflammation (Inflammations) 10/2020 - 09/2007
4	Leukemia 02/2010 - 09/2002
3	Hydronephrosis 11/2019 - 10/2016
3	Chronic Kidney Failure (Chronic Renal Failure) 01/2019 - 01/2012
3	Cystitis 01/2018 - 05/2013
3	Melanoma (Melanoma, Malignant) 04/2010 - 07/2004
2	Nephrotic Syndrome (Syndrome, Nephrotic) 04/2022 - 11/2012
2	Neurogenic Urinary Bladder (Bladder, Neurogenic) 11/2019 - 01/2019
2	Vesico-Ureteral Reflux (Vesicoureteral Reflux) 11/2019 - 10/2016
2	Bacteriuria 01/2019 - 01/2015
2	Segmental glomerulosclerosis 01/2018 - 01/2011
2	Fibrosis (Cirrhosis) 01/2017 - 01/2015
2	Infertility (Sterility) 11/2015 - 01/2015
2	Urolithiasis 01/2015 - 05/2013
2	Graft vs Host Disease (Graft-Versus-Host Disease) 10/2006 - 07/2004
1	Proteinuria 04/2022
1	Hypoalbuminemia 04/2022
1	Nephrosis 04/2022
1	Albuminuria 11/2019
1	Peritonitis 01/2019
1	Hyperglycemia 12/2018
1	Insulin Resistance 12/2018
1	Abscess 01/2018
1	Hereditary Nephritis (Alport Syndrome) 01/2018
1	Communicable Diseases (Infectious Diseases) 03/2016
1	Fever (Fevers) 03/2016
1	Acute Kidney Injury (Acute Renal Failure) 03/2016
1	Wounds and Injuries (Trauma) 03/2016
1	Leukocytosis (Pleocytosis) 03/2016
1	Spasm (Spasms) 03/2016
1	Cerebral Palsy (Spastic Diplegia) 03/2016
1	Hypotension (Low Blood Pressure) 03/2016

Drug/Important Bio-Agent (IBA)

9	Antimicrobial PeptidesIBA 01/2019 - 01/2012
6	Ribonuclease 7IBA 01/2019 - 01/2015
6	Proteins (Proteins, Gene)FDA Link 01/2015 - 02/2005
5	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2019
5	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 02/2005
4	Messenger RNA (mRNA)IBA 01/2015 - 01/2013
4	Interferon-gamma (Interferon, gamma)IBA 04/2010 - 04/2005
3	InterleukinsIBA 10/2020 - 10/2007
3	Ribonucleases (Ribonuclease)IBA 01/2019 - 01/2015
3	Pancreatic Ribonuclease (Ribonuclease A)IBA 01/2019 - 01/2015
3	Antigen-Antibody Complex (Immune Complex)IBA 01/2018 - 09/2010
3	LigandsIBA 09/2010 - 04/2003
3	CytokinesIBA 04/2010 - 04/2003
2	CreatinineIBA 01/2021 - 11/2019
2	Interleukin-6 (Interleukin 6)IBA 10/2020 - 01/2018
2	Biological ProductsIBA 01/2019 - 10/2014
2	Eosinophil Cationic ProteinIBA 01/2019 - 01/2019
2	Insulin (Novolin)FDA Link 12/2018 - 01/2016
2	StruviteIBA 01/2015 - 05/2013
2	Adenosine Monophosphate (AMP)IBA 01/2015 - 01/2012
2	Suppressor of Cytokine Signaling ProteinsIBA 04/2010 - 04/2007
2	MonokinesIBA 10/2007 - 04/2005
2	Interleukin-15 (Interleukin 15)IBA 10/2006 - 10/2004
2	MethyltransferasesIBA 07/2005 - 02/2005
2	Histone Deacetylases (Histone Deacetylase)IBA 07/2005 - 02/2005
1	CholesterolIBA 04/2022
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 04/2022
1	Pioglitazone (Actos)FDA Link 04/2022
1	PotassiumIBA 01/2021
1	Cytokine Receptor gp130IBA 10/2020
1	Cholinergic Antagonists (Anticholinergics)IBA 11/2019
1	AlbuminsIBA 11/2019
1	Peptides (Polypeptides)IBA 01/2019
1	Insulin ReceptorIBA 12/2018
1	UroplakinsIBA 10/2018
1	AndrogensIBA 01/2018
1	Amino Acids FDA Link 01/2018
1	Cysteine (L-Cysteine)FDA Link 01/2018
1	GuanineIBA 01/2018
1	NucleotidesIBA 01/2018
1	Phenobarbital (Luminal)FDA Link 01/2018
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2018
1	ThymineIBA 01/2018
1	Collagen Type IV (Type IV Collagen)IBA 01/2018
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018
1	MicroRNAs (MicroRNA)IBA 10/2016
1	DefensinsIBA 10/2016
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2016
1	Baclofen FDA LinkGeneric 03/2016
1	Vancomycin FDA LinkGeneric 03/2016
1	Therapeutic UsesIBA 03/2016
1	gamma-Aminobutyric Acid (GABA)IBA 03/2016

Therapy/Procedure

6	Therapeutics 01/2020 - 09/2002
2	Renal Dialysis (Hemodialysis) 03/2016 - 11/2014
2	Cystostomy (Suprapubic Cystostomy) 05/2013 - 01/2012
1	Peritoneal Dialysis 01/2019
1	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2019
1	Ligation 10/2018
1	Immunomodulation 01/2017
1	Antibiotic Prophylaxis 10/2016
1	Critical Care (Surgical Intensive Care) 03/2016
1	Artificial Respiration (Mechanical Ventilation) 03/2016